Molecular Umbrella Transport: Exceptions to the Classic Size/Lipophilicity Rule

Exceptions That Prove the Rule

“The exception that proves the rule...” This often-misunderstood English language idiom, at least in its “loose rhetorical sense” [1], is highly applicable to the transmission from providers infected with blood-borne pathogens to their patients (ie, the rarity of these events helps characterize and define the miniscule risk for these transmissions in the practice of modern medicine). Decades of...

Correction to Molecular Umbrella–Amphotericin B Conjugates

A ll sterols that appear on the right side of each molecular umbrella framework shown in the Abstract, Text, and Table of Contents should have been drawn with the natural stereochemistry of cholic acid shown below and not that of its enantiomer: This is an open access article published under an ACS AuthorChoice License, which permits copying and redistribution of the article or any adaptations ...

An Introduction to Umbrella Reviews

سخن سردبیر Editorial مجله دانشگاه علوم پزشکی رفسنجان دوره هجدهم، مهر 1398، 622-621     درآمدی بر مرور چتری An Introduction to Umbrella Reviews   محسن رضائیان[1]   M. Rezaeian   آیونیدیس (Ioannidis) در سال 2009 میلادی توضیح روشنی از مرور چتری (Umbrella review) ارائه کرده است. وی توضیح می‌دهد که یک مرور چتری به طور نظام‌مند به جمع‌بندی و ارزشیابی نتایج حاصل از چندین مرور نظام‌مند و ی...

Molecular Umbrella–Amphotericin B Conjugates

A tetrawalled and an octawalled molecular umbrella conjugate of amphotericin B (AmB) have been synthesized. Both conjugates exhibit high water solubility, a low tendency to aggregate, negligible hemolytic activity at 100 μM, and an ability to release a derivative of AmB under reducing conditions that exhibits high antifungal activity. Whereas the larger, octawalled conjugate shows slight adsorp...

Exceptions to the Rule: Curing the Law's Failure to Protect Intersex Infants